脊柱转移瘤的治疗：有中等质量证据表明，与单独放疗相比，加用大剂量皮质类固醇放疗治疗 6 个月后可改善行走的几率。[77]Sorensen S, Helweg-Larsen S, Mouridsen H, et al. Effect of high-dose dexamethasone in carcinomatous metastatic spinal cord compression treated with radiotherapy: a randomised trial. Eur J Cancer. 1994;30A(1):22-7.http://www.ncbi.nlm.nih.gov/pubmed/8142159?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
脊柱转移瘤的治疗：有中等质量证据表明，与单独放疗相比，加用大剂量皮质类固醇放疗治疗 6 个月后可改善行走的几率。[77]Sorensen S, Helweg-Larsen S, Mouridsen H, et al. Effect of high-dose dexamethasone in carcinomatous metastatic spinal cord compression treated with radiotherapy: a randomised trial. Eur J Cancer. 1994;30A(1):22-7.http://www.ncbi.nlm.nih.gov/pubmed/8142159?tool=bestpractice.com
脊柱转移瘤的治疗：有中等质量证据表明，对于治疗转移性癌症引起的脊髓压迫症患者，手术后放射治疗比单独放射更有效。[85]Patchell RA, Tibbs PA, Regine WF, et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet. 2005 Aug 20-26;366(9486):643-8.http://www.ncbi.nlm.nih.gov/pubmed/16112300?tool=bestpractice.com[86]Putz C, van Middendorp JJ, Pouw MH, et al. Malignant cord compression: a critical appraisal of prognostic factors predicting functional outcome after surgical treatment. J Craniovertebr Junction Spine. 2010 Jul;1(2):67-73.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075832http://www.ncbi.nlm.nih.gov/pubmed/21572627?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
脊柱转移瘤的治疗：有中等质量证据表明，对于治疗转移性癌症引起的脊髓压迫症患者，手术后放射治疗比单独放射更有效。[85]Patchell RA, Tibbs PA, Regine WF, et al. Direct decompressive surgical resection in the treatment of spinal cord compression caused by metastatic cancer: a randomised trial. Lancet. 2005 Aug 20-26;366(9486):643-8.http://www.ncbi.nlm.nih.gov/pubmed/16112300?tool=bestpractice.com[86]Putz C, van Middendorp JJ, Pouw MH, et al. Malignant cord compression: a critical appraisal of prognostic factors predicting functional outcome after surgical treatment. J Craniovertebr Junction Spine. 2010 Jul;1(2):67-73.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075832http://www.ncbi.nlm.nih.gov/pubmed/21572627?tool=bestpractice.com
椎间盘突出的治疗：有低质量证据表明硬膜外皮质类固醇治疗椎间盘突出有效。[72]Buttermann GR. Treatment of lumbar disc herniation: epidural steroid injection compared with discectomy. A prospective, randomized study. J Bone Joint Surg Am. 2004 Apr;86-A(4):670-9.http://www.ncbi.nlm.nih.gov/pubmed/15069129?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
椎间盘突出的治疗：有低质量证据表明硬膜外皮质类固醇治疗椎间盘突出有效。[72]Buttermann GR. Treatment of lumbar disc herniation: epidural steroid injection compared with discectomy. A prospective, randomized study. J Bone Joint Surg Am. 2004 Apr;86-A(4):670-9.http://www.ncbi.nlm.nih.gov/pubmed/15069129?tool=bestpractice.com
乳腺癌脊柱转移的治疗：有低质量证据表明放疗可改善治疗效果，但是治疗时机很重要，因为如果运动功能严重退化出现在放疗开始之前，则只有少于 10% 的人能重新行走。[75]Rades D, Blach M, Nerreter V, et al. Metastatic spinal cord compression. Influence of time between onset of motoric deficits and start of irradiation on therapeutic effect. Strahlenther Onkol. 1999 Aug;175(8):378-81.http://www.ncbi.nlm.nih.gov/pubmed/10481768?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
乳腺癌脊柱转移的治疗：有低质量证据表明放疗可改善治疗效果，但是治疗时机很重要，因为如果运动功能严重退化出现在放疗开始之前，则只有少于 10% 的人能重新行走。[75]Rades D, Blach M, Nerreter V, et al. Metastatic spinal cord compression. Influence of time between onset of motoric deficits and start of irradiation on therapeutic effect. Strahlenther Onkol. 1999 Aug;175(8):378-81.http://www.ncbi.nlm.nih.gov/pubmed/10481768?tool=bestpractice.com
