BMJ Best Practice
最后审核时间： 十月 2018
最近更新时间： 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 长期以及进行性症状
  • 头痛
  • 垂体卒中
全部具体信息

其他诊断因素

  • 增加的中央型肥胖
  • 肌肉减少
  • 便秘
  • 不耐受寒冷
全部具体信息

危险因素

  • 多发性内分泌肿瘤1型（MEN-1）
  • 家族性孤立性垂体腺瘤（FIPA）
  • Carney综合征（CNC）
全部具体信息

诊断性检查

首要检查

  • 催乳素
  • 生长激素刺激试验（ITT或GHRH/精氨酸）
  • 胰岛素样生长因子-1（IGF-1）
  • 促黄体激素（LH）、卵泡刺激素（FSH）
全部具体信息

需要考虑的检查

  • 血脂
  • Humphrey或Goldmann正式视野测试
  • 免疫组织化学染色
全部具体信息

治疗流程

急性

垂体卒中

疾病持续状态

微小腺瘤

没有肿块压迫症状和不毗邻视交叉的巨大腺瘤

无肿块压迫症状但毗邻视交叉的巨大腺瘤

有肿块压迫症状的巨大腺瘤

贡献者

作者 查看所有

Assistant Professor of Neurosurgery

Otolaryngology and Internal Medicine

Co-Director, USC Pituitary Center

Co-Director, USC Radiosurgery Center

Director, USC Endoscopic Skull Base Surgery Program

Keck Medicine of USC

University of Southern California

Los Angeles

CA

利益冲突披露
GZ declares that he has no competing interests.

Associate Professor of Clinical Medicine

Co-director, USC Pituitary Center

Keck Medicine at USC

University of Southern California

Los Angeles

CA

利益冲突披露
JC declares that he is a paid member of the advisory boards at Pfizer and Chiasma, and he has received speaker honorarium from Novartis. JC also holds unpaid positions on the editorial board of Pituitary and is a Senior Editor for Endocrine, Diabetes, and Metabolism Case Reports. JC is also a Principal Investigator in the research he undertakes and which is funded by: Novo Nordisk, Chiasma, Novartis, and Pfizer.

Dr Gabriel Zada and Dr John Carmichael would like to gratefully acknowledge Dr Israel Orija and Dr Amir H. Hamrahian, previous contributors to this monograph. IO and AH declare that they have no competing interests.

同行评议专家 查看所有

Consultant Endocrinologist

Newcastle Hospitals NHS Foundation Trust

Royal Victoria Infirmary

Newcastle

UK

利益冲突披露
AJ declares that he has no competing interests.

Reader in Neuropathology and Honorary Consultant in Neuropathology

Neuropathology Unit

Department of Clinical Neuroscience

Division of Neuroscience and Mental Health

Faculty of Medicine

Imperial College

London

UK

利益冲突披露
FR declares that he has no competing interests.

Associate Professor of Medicine

Division of Endocrinology

Johns Hopkins University

Baltimore

MD

利益冲突披露
RS declares that he has no competing interests.

Professor and Chief

Chairman

Department of Endocrinology, Diabetes and Metabolism

Cleveland Clinic

Cleveland

OH

利益冲突披露
LK declares that he has no competing interests.

Professor of Medicine and Oncology

University of Toronto

Toronto

Ontario

Canada

利益冲突披露
SE declares that he has no competing interests.

Associate Professor

Stanford University

Palo Alto

CA

利益冲突披露
LK declares that he has no competing interests.

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