BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 复发性感染
  • 肺炎链球菌或嗜血杆菌感染
  • 非典型病原体感染

其他诊断因素

  • 休学/休工
  • 生长发育迟滞
  • 腹泻
  • 鼻窦炎

危险因素

  • 幼儿期和成年期早期(原发性疾病)
  • 老年(继发性疾病)
  • 男性性别
  • 原发性免疫缺陷阳性家族史

诊断性检查

首要检查

  • 全血细胞计数 (FBC)
  • 血清 IgG
  • 血清 IgA
  • 血清 IgM
全部具体信息

需要考虑的检查

  • 流式细胞术:淋巴细胞亚群
  • 特异性抗微生物抗体
  • 检查免疫反应
  • IgG 亚型
全部具体信息

治疗流程

贡献者

Consultant Immunologist

Frimley Park & St Thomas' Hospital

Frimley

Surrey

UK

利益冲突披露
MYK serves on the advisory board for Allergy Therapeutics, which manufactures allergy immunotherapy products and allergy skin testing products.

Dr Mohammed Yousuf Karim would like to gratefully acknowledge Dr Patrick Yong and Dr Zoe Adhya, previous contributors to this monograph. PY and ZA declare that they have no competing interests.

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Associate Professor of Pediatrics

University of New South Wales

Department of Immunology and Infectious Diseases

Sydney Children's Hospital

Sydney

NSW

Australia

利益冲突披露
JBZ declares that he has no competing interests.

Professor of Medicine and Pediatrics

Immunology Institute

Mount Sinai School of Medicine

New York

NY

利益冲突披露
CCR is an author of several references cited in the monograph.

Honorary Clinical Scientist

UCL Centre for Primary Immunodeficiency

University College London Medical School

Department of Immunology

Royal Free Hospital

London

UK

利益冲突披露
DW declares that he has no competing interests.

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