死亡率减低：有高质量证据表明，胸部放疗加上化疗比单纯化疗在减低局限期 SCLC 患者 3 年死亡率上更为有效。[39]Pignon JP, Arriagada R, Ihde DC, et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med. 1992;327:1618-1624.http://www.ncbi.nlm.nih.gov/pubmed/1331787?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
死亡率减低：有高质量证据表明，胸部放疗加上化疗比单纯化疗在减低局限期 SCLC 患者 3 年死亡率上更为有效。[39]Pignon JP, Arriagada R, Ihde DC, et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med. 1992;327:1618-1624.http://www.ncbi.nlm.nih.gov/pubmed/1331787?tool=bestpractice.com
死亡率减低：有高质量证据表明，一天两次放疗比一天一次更为有效。[42]Auperin A, Arriagada R, Pignon JP, et al; Prophylactic Cranial Irradiation Overview Collaborative Group. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. N Engl J Med. 1999;341:476-484.http://www.nejm.org/doi/full/10.1056/NEJM199908123410703#t=articlehttp://www.ncbi.nlm.nih.gov/pubmed/10441603?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
死亡率减低：有高质量证据表明，一天两次放疗比一天一次更为有效。[42]Auperin A, Arriagada R, Pignon JP, et al; Prophylactic Cranial Irradiation Overview Collaborative Group. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. N Engl J Med. 1999;341:476-484.http://www.nejm.org/doi/full/10.1056/NEJM199908123410703#t=articlehttp://www.ncbi.nlm.nih.gov/pubmed/10441603?tool=bestpractice.com
死亡率减低：有一定证据，表明早期放疗比晚期放疗更为有效。[40]Fried DB, Morris DE, Poole C, et al. Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer. J Clin Oncol. 2004;22:4837-4845.http://www.ncbi.nlm.nih.gov/pubmed/15570087?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
死亡率减低：有一定证据，表明早期放疗比晚期放疗更为有效。[40]Fried DB, Morris DE, Poole C, et al. Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer. J Clin Oncol. 2004;22:4837-4845.http://www.ncbi.nlm.nih.gov/pubmed/15570087?tool=bestpractice.com
