BMJ Best Practice
最后审核时间： 十月 2018
最近更新时间： 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 膳食调查时考虑维生素 C 缺乏症
  • 全身症状
  • 容易发生青紫或出血
  • 步态障碍或腿痛
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其他诊断因素

  • 吞咽困难
  • 脱发
  • Sicca样或 Sjogren样综合征
  • 杵状甲
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危险因素

  • 饥荒和难民人群
  • 只喝牛奶的婴儿
  • 吸烟
  • 手术
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诊断性检查

首要检查

  • FBC 和外周血涂片
  • 血清抗坏血酸
  • 白细胞抗坏血酸
  • 全血抗坏血酸
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需要考虑的检查

  • 儿科病例膝盖、手腕和长骨 MRI检查
  • 骨髓活检
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治疗流程

推断

高风险或有症状的人群

贡献者

作者 查看所有

James M. Noble MD, MS, CPH

Assistant Professor of Clinical Neurology

Neurology Clerkship Director

Department of Neurology

Harlem Hospital Center

Columbia University College of Physicians and Surgeons

New York

NY

利益冲突披露
JMN declares that he has no competing interests.
Marc C. Patterson MD

Chair

Division of Child and Adolescent Neurology

Professor of Neurology, Pediatrics, and Medical Genetics

Director

Child Neurology Training Program

Mayo Clinic

Rochester

MN

利益冲突披露
MCP declares that he has received consultancy fees from Actelion, Alexion, Agios, Novartis, Orphazyme, Shire, and Vtesse; travel and accommodation expenses from Actelion, Alexion, Agios, and Shire; a grant from Actelion; honoraria from Journal of Child Neurology/Child Neurology Open and Journal of Inherited Metabolic Disease; and royalties from Up-to-Date.

Endocrinologist

Molecular and Clinical Nutrition Section

Digestive Diseases Branch

National Institute of Diabetes and Digestive and Kidney Diseases

Bethesda

MD

利益冲突披露
SP declares that he has no competing interests.

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