检查 需要使用选择性培养基如亚碲酸血琼脂、加强型莱夫勒、霍伊尔、米勒或廷德尔培养基,所以需要提前准备及与微生物学家联络。[16]American Academy of Pediatrics Committee on Infectious Diseases. Diphtheria. In: Kimberlin DW, Brady MT, Jackson MA, Long SS, eds. Red Book: 2018 report of the Committee on Infectious Diseases. 31st ed. Itasca, IL: American Academy of Pediatrics; 2018:319-23.https://redbook.solutions.aap.org/chapter.aspx?sectionid=189640082&bookid=2205[28]Public Health England. Public health control and management of diphtheria (in England and Wales). Mar 2015 [internet publication].https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/416108/Diphtheria_Guidelines_Final.pdf
培养物应取自疑似白喉患者及其密切接触者的鼻和咽拭子。 在可能的情况下,应在假膜下方取样。
如果高度怀疑白喉,应从患者及所有密切接触者获得拭子。 即使已经开始抗生素治疗,也可以进行培养,尽管在这种情况下培养更有可能不成功。[1]Centers for Disease Control and Prevention. Manual for the surveillance of vaccine-preventable diseases. Chapter 1: diphtheria. Mar 2018 [internet publication].https://www.cdc.gov/vaccines/pubs/surv-manual/chpt01-dip.html