BMJ Best Practice
最后审核时间： 十月 2018
最近更新时间： 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 男性
  • 有炎症性肠病病史
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其他诊断因素

  • 年龄在40多或50多岁
  • 腹痛
  • 皮肤瘙痒
  • 乏力
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危险因素

  • 男性
  • 炎症性肠病（IBD）
  • 遗传易感性
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诊断性检查

首要检查

  • 血清碱性磷酸酶
  • 血清γ-GT
  • 血清转氨酶（AST，ALT）
  • 血清总胆红素
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需要考虑的检查

  • 血清免疫球蛋白
  • 血清IgG4
  • 肝脏铜含量
  • 尿铜含量
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治疗流程

急性

疾病早期

终末期肝病

贡献者

作者 查看所有

Director of Education

Digestive Disease Institute

Virginia Mason Medical Center

Seattle

WA

利益冲突披露
SIG declares that he has no competing interests.

Dr S. Ian Gan would like to gratefully acknowledge Dr Kris V. Kowdley and Dr Christine Schlenker, the previous contributors to this monograph. KVK is a member of the speakers bureau of Axcan Pharma, manufacturer of Urso250 and Urso Forte, and gives one or two lectures a year on treatment of cholestatic liver diseases. KVK has also received funding from the NIH for a research study of Urso in PSC. CS declares that she has no competing interests.

同行评议专家 查看所有

Associate Professor of Medicine

Division of Digestive and Liver Diseases

University of Texas Southwestern Medical Center

Dallas

TX

利益冲突披露
MM is an author of a reference cited in this monograph.

Consultant Physician

Liver Unit

Queen Elizabeth Hospital

Birmingham

UK

利益冲突披露
JN declares that he has no competing interests.

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