疗效：有中等级别的证据表明，治疗性ERCP可改善胆汁淤积，瘙痒，以及生存率。[56]Gluck M, Cantone NR, Brandaburr JJ, et al. A twenty-year experience with endoscopic therapy for symptomatic primary sclerosing cholangitis. J Clin Gastroenterol. 2008;42:1032-1039.http://www.ncbi.nlm.nih.gov/pubmed/18580600?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
疗效：有中等级别的证据表明，治疗性ERCP可改善胆汁淤积，瘙痒，以及生存率。[56]Gluck M, Cantone NR, Brandaburr JJ, et al. A twenty-year experience with endoscopic therapy for symptomatic primary sclerosing cholangitis. J Clin Gastroenterol. 2008;42:1032-1039.http://www.ncbi.nlm.nih.gov/pubmed/18580600?tool=bestpractice.com
疗效：有中等级别的证据表明，肝移植患者的10年生存率为70%。[62]Graziadei IW. Wiesner RH, Marotta PJ, et al. Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis. Hepatology. 1999;30:1121-1127.http://www.ncbi.nlm.nih.gov/pubmed/10534330?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
疗效：有中等级别的证据表明，肝移植患者的10年生存率为70%。[62]Graziadei IW. Wiesner RH, Marotta PJ, et al. Long-term results of patients undergoing liver transplantation for primary sclerosing cholangitis. Hepatology. 1999;30:1121-1127.http://www.ncbi.nlm.nih.gov/pubmed/10534330?tool=bestpractice.com
疗效：低级别证据表明胆汁酸螯合剂提供有效缓解因黄疸导致的瘙痒。[52]Carey JB Jr, Williams G. Relief of the pruritus of jaundice with a bile-acid sequestering resin. JAMA. 1961;176:432-435.http://www.ncbi.nlm.nih.gov/pubmed/13690773?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
疗效：低级别证据表明胆汁酸螯合剂提供有效缓解因黄疸导致的瘙痒。[52]Carey JB Jr, Williams G. Relief of the pruritus of jaundice with a bile-acid sequestering resin. JAMA. 1961;176:432-435.http://www.ncbi.nlm.nih.gov/pubmed/13690773?tool=bestpractice.com
疗效：有低级别的循证医学证据表明，免疫抑制剂治疗PSC是无效的。[77]Michaels A, Levy C. The medical management of primary sclerosing cholangitis. Medscape J Med. 2008;10:61.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329756/http://www.ncbi.nlm.nih.gov/pubmed/18449341?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
疗效：有低级别的循证医学证据表明，免疫抑制剂治疗PSC是无效的。[77]Michaels A, Levy C. The medical management of primary sclerosing cholangitis. Medscape J Med. 2008;10:61.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329756/http://www.ncbi.nlm.nih.gov/pubmed/18449341?tool=bestpractice.com
