慢性心房颤动

血管紧张素转化酶抑制剂、他汀类药物和特定鱼类中富含的特殊膳食脂质成分，可降低心房颤动发病率。[42]Healey JS, Baranchuk A, Crystal E, et al. Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis. J Am Coll Cardiol. 2005 Jun 7;45(11):1832-9.http://www.ncbi.nlm.nih.gov/pubmed/15936615?tool=bestpractice.com[43]Wachtell K, Lehto M, Gerdts E, et al. Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) study. J Am Coll Cardiol. 2005 Mar 1;45(5):712-9.http://www.ncbi.nlm.nih.gov/pubmed/15734615?tool=bestpractice.com[44]Olsson LG, Swedberg K, Ducharme A, et al. Atrial fibrillation and risk of clinical events in chronic heart failure with and without left ventricular systolic dysfunction: results from the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) program. J Am Coll Cardiol. 2006 May 16;47(10):1997-2004.http://www.onlinejacc.org/content/47/10/1997http://www.ncbi.nlm.nih.gov/pubmed/16697316?tool=bestpractice.com[45]Young-Xu Y, Jabbour S, Goldberg R, et al. Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease. Am J Cardiol. 2003 Dec 15;92(12):1379-83.http://www.ncbi.nlm.nih.gov/pubmed/14675569?tool=bestpractice.com[46]Siu CW, Lau CP, Tse HF. Prevention of atrial fibrillation recurrence by statin therapy in patients with lone atrial fibrillation after successful cardioversion. Am J Cardiol. 2003 Dec 1;92(11):1343-5.http://www.ncbi.nlm.nih.gov/pubmed/14636918?tool=bestpractice.com[47]Mozaffarian D, Psaty BM, Rimm EB, et al. Fish intake and risk of incident atrial fibrillation. Circulation. 2004 Jul 27;110(4):368-73.http://circ.ahajournals.org/content/110/4/368.fullhttp://www.ncbi.nlm.nih.gov/pubmed/15262826?tool=bestpractice.com 对于接受心脏手术的患者和心房颤动高危患者来说，术前使用 β 受体阻滞剂或胺碘酮可降低术后房颤的发生率。[3]January CT, Wann LS, Alpert JS, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014 Dec 2;64(21):e1-76.http://content.onlinejacc.org/article.aspx?articleid=1854231http://www.ncbi.nlm.nih.gov/pubmed/24685669?tool=bestpractice.com[5]Paciaroni M, Agnelli G, Caso V, et al. Atrial fibrillation in patients with first-ever stroke: frequency, antithrombotic treatment before the event and effect on clinical outcome. J Thromb Haemost. 2005 Jun;3(6):1218-23.http://onlinelibrary.wiley.com/doi/10.1111/j.1538-7836.2005.01344.x/fullhttp://www.ncbi.nlm.nih.gov/pubmed/15892862?tool=bestpractice.com[48]Fuster V, Rydén LE, Cannom DS, et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation. Circulation. 2006 Aug 15;114(7):e257-354.http://circ.ahajournals.org/cgi/content/full/114/7/e257http://www.ncbi.nlm.nih.gov/pubmed/16908781?tool=bestpractice.com [ ]What are the effects of pharmacological interventions to prevent atrial fibrillation after heart surgery?https://cochranelibrary.com/cca/doi/10.1002/cca.922/full显示答案 [ ]How does amiodarone compare with placebo for the prevention of sudden cardiac death in at-risk adults?https://cochranelibrary.com/cca/doi/10.1002/cca.1289/full显示答案

减轻体重并进行强化危险因素管理已被证明可缓解心房纤颤症状负担和严重程度，并可引起有益的心脏重塑。[130]Abed HS, Wittert GA, Leong DP, et al. Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial. JAMA. 2013;310:2050-2060.http://jama.jamanetwork.com/article.aspx?articleid=1779533http://www.ncbi.nlm.nih.gov/pubmed/24240932?tool=bestpractice.com