中位生存期改善：有低质量证据显示肺癌导致的近端气道阻塞的患者，接受包括大剂量支气管内放疗的多方式治疗后，中位生存期增加到7.8个月，而历史对照组中位生存期为3.9个月。[115]Manali ED, Stathopoulos GT, Gildea TR, et al. High dose-rate endobronchial radiotherapy for proximal airway obstruction due to lung cancer: 8-year experience of a referral center. Cancer Biother Radiopharm. 2010;25:207-213.http://www.ncbi.nlm.nih.gov/pubmed/20423234?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
中位生存期改善：有低质量证据显示肺癌导致的近端气道阻塞的患者，接受包括大剂量支气管内放疗的多方式治疗后，中位生存期增加到7.8个月，而历史对照组中位生存期为3.9个月。[115]Manali ED, Stathopoulos GT, Gildea TR, et al. High dose-rate endobronchial radiotherapy for proximal airway obstruction due to lung cancer: 8-year experience of a referral center. Cancer Biother Radiopharm. 2010;25:207-213.http://www.ncbi.nlm.nih.gov/pubmed/20423234?tool=bestpractice.com
症状改善：低质量证据显示气道支架置入伴或不伴放射治疗可以明显改善体力状态差患者的症状。[121]Razi SS, Lebovics RS, Schwartz G, et al. Timely airway stenting improves survival in patients with malignant central airway obstruction. Ann Thorac Surg. 2010;90:1088-1093.http://www.ncbi.nlm.nih.gov/pubmed/20868793?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
症状改善：低质量证据显示气道支架置入伴或不伴放射治疗可以明显改善体力状态差患者的症状。[121]Razi SS, Lebovics RS, Schwartz G, et al. Timely airway stenting improves survival in patients with malignant central airway obstruction. Ann Thorac Surg. 2010;90:1088-1093.http://www.ncbi.nlm.nih.gov/pubmed/20868793?tool=bestpractice.com
进展性肺癌支架置入后的生存期：低质量证据显示，与体力状态差的对照组相比，中等体力状态患者进行气道支架置入改善了生存期（8个月 vs 3个月）。[121]Razi SS, Lebovics RS, Schwartz G, et al. Timely airway stenting improves survival in patients with malignant central airway obstruction. Ann Thorac Surg. 2010;90:1088-1093.http://www.ncbi.nlm.nih.gov/pubmed/20868793?tool=bestpractice.com[123]Furukawa K, Ishida J, Yamaguchi G, et al. The role of airway stent placement in the management of tracheobronchial stenosis caused by inoperable advanced lung cancer. Surg Today. 2010;40:315-320.http://www.ncbi.nlm.nih.gov/pubmed/20339985?tool=bestpractice.com
系统评价或者受试者＞200名的随机对照临床试验（RCT）。
进展性肺癌支架置入后的生存期：低质量证据显示，与体力状态差的对照组相比，中等体力状态患者进行气道支架置入改善了生存期（8个月 vs 3个月）。[121]Razi SS, Lebovics RS, Schwartz G, et al. Timely airway stenting improves survival in patients with malignant central airway obstruction. Ann Thorac Surg. 2010;90:1088-1093.http://www.ncbi.nlm.nih.gov/pubmed/20868793?tool=bestpractice.com[123]Furukawa K, Ishida J, Yamaguchi G, et al. The role of airway stent placement in the management of tracheobronchial stenosis caused by inoperable advanced lung cancer. Surg Today. 2010;40:315-320.http://www.ncbi.nlm.nih.gov/pubmed/20339985?tool=bestpractice.com
