分裂情感性精神障碍的诊断标准在过去几十年间有很大变动,影响了开展长期流行病学研究的能力。
因此,没有关于分裂情感性精神障碍患病率或发病率的大规模流行病学数据。
据估计,分裂情感性精神障碍不如精神分裂症常见。[1]American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., (DSM-5). Washington, DC: American Psychiatric Publishing; 2013.
发病年龄:30% 病例的发病年龄小于 25 岁,还有 30% 病例的发病年龄介于 25 与 35 岁,另外 30% 病例的发病年龄大于 35 岁。[5]Marneros A, Deister A, Rohde A. Psychopathological and social status of patients with affective, schizophrenic and schizoaffective disorders after long-term course. Acta Psychiatr Scand. 1990 Nov;82(5):352-8.http://www.ncbi.nlm.nih.gov/pubmed/2281805?tool=bestpractice.com
性别分布:似乎在女性中更常见。[6]Abrams DJ, Rojas DC, Arciniegas DB. Is schizoaffective disorder a distinct categorical diagnosis? A critical review of the literature. Neuropsychiatr Dis Treat. 2008 Dec;4(6):1089-109.http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646642/?tool=pubmedhttp://www.ncbi.nlm.nih.gov/pubmed/19337453?tool=bestpractice.com
在区域性研究中,分裂情感性精神障碍的终生患病率为 0.32% 至 1.1% 不等。[7]Perala J, Suvisaari J, Saarni SI, et al. Lifetime prevalence of psychotic and bipolar I disorders in a general population. Arch Gen Psychiatry. 2007 Jan;64(1):19-28.https://jamanetwork.com/journals/jamapsychiatry/fullarticle/209973http://www.ncbi.nlm.nih.gov/pubmed/17199051?tool=bestpractice.com[8]Scully PJ, Owens JM, Kinsella A, et al. Schizophrenia, schizoaffective and bipolar disorder within an epidemiologically complete, homogeneous population in rural Ireland: small area variation in rate. Schizophr Res. 2004 Apr 1;67(2-3):143-55.http://www.ncbi.nlm.nih.gov/pubmed/14984873?tool=bestpractice.com
估计分裂情感性精神障碍占精神病入院病例的 10% 至 30%。[9]Azorin JM, Kaladjian A, Fakra E. Current issues on schizoaffective disorder [in French]. Encephale. 2005 May-Jun;31(3):359-6.http://www.ncbi.nlm.nih.gov/pubmed/16142051?tool=bestpractice.com