BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 八月 2018

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 生殖器溃疡
  • 淋巴结肿大
  • 弥漫性皮疹

其他诊断因素

  • 口腔溃疡
  • 无症状(潜伏梅毒)
  • 口腔溃疡
  • 无症状(潜伏梅毒)

危险因素

  • 与受感染个体性接触
  • 男男性行为者
  • 非法用药
  • 职业性工作者

诊断性检查

首要检查

  • 病灶处拭子暗视野显微镜检查
  • 血清梅毒螺旋体酶免疫测定 (EIA)
  • 血清螺旋体颗粒凝集试验 (serum T pallidum particle agglutination, TPPA)
  • 血清螺旋体血凝集试验 (serum T pallidum haemagglutination, TPHA)
全部具体信息

需要考虑的检查

  • 腰椎穿刺术,CSF 分析
  • 胸部 X 线检查(CXR)
  • 超声心动图
  • 脑部 CT
全部具体信息

新兴检查

  • 密螺旋体或密螺旋体/非密螺旋体抗体联合床旁 (POC) 检测
  • 梅毒螺旋体 PCR (直接从溃疡病灶处采集样本)
全部具体信息

治疗流程

贡献者

Professor and Chair

Department of Pediatrics

University of Connecticut School of Medicine

Hartford

CT

利益冲突披露
JCS is the author of references cited in this monograph.

Assistant Professor of Pediatrics

Adjunct Assistant Professor of Pharmacy

Department of Pediatrics

University of Connecticut School of Medicine

Hartford

CT

利益冲突披露
NB declares that he has no competing interests.

Research Associate

CIDEIM

Cali

Columbia

利益冲突披露
AC declares that she has no conflicting interests.

Dr Juan C. Salazar, Dr Nicholas Bennett, and Dr Adriana Cruz would like to gratefully acknowledge Patrick French and Nooshin Barmania, previous contributors to this monograph. PF is an author of a reference cited in this monograph. NB declares that she has no competing interests.

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Associate Professor of Medicine

University of Southern California

Keck School of Medicine

Los Angeles

CA

利益冲突披露
RAL declares that he has no competing interests.

Assistant Professor of Medicine

Harvard Medical School

Director of Research

Global Health Delivery Project

Harvard School of Public Health

Boston

MA

利益冲突披露
WR declares that he has no competing interests.

Consultant Paediatrician

Croydon University Hospital

Croydon

UK

利益冲突披露
JH declares that she has no competing interests.

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