BMJ Best Practice
最后审核时间: 六月 2019
最近更新时间: 三月 2019

小结

定义

病史和查体

关键诊断因素

  • 颧部(蝶形)红斑
  • 光敏性皮疹
  • 盘状红斑

其他诊断因素

  • 疲劳
  • 体重减轻
  • 发热
  • 口腔溃疡

危险因素

  • 女性
  • 15-45岁
  • 在美国和欧洲的亚裔/非洲裔
  • 药物

诊断性检查

首要检查

  • 全血细胞计数和分类计数
  • 活化PTT
  • 尿素和电解质
  • 红细胞沉降率 (ESR) 和 C 反应蛋白 (CRP)
全部具体信息

需要考虑的检查

  • 血液和尿液培养
  • 抗磷脂抗体
  • Coombs 试验
  • 24小时尿液检测蛋白或随机尿检测蛋白/肌酐比
全部具体信息

治疗流程

贡献者

Consultant Rheumatologist

Wishaw General Hospital

Wishaw

UK

利益冲突披露
MMC declares that she has no competing interests.

Consultant Physician and Rheumatologist

Department of Rheumatology

Glasgow Royal Infirmary

Glasgow

UK

利益冲突披露
RM holds shares in GSK to the value less than £12,000.

Dr Meng May Chee and Dr Rajan Madhok would like to gratefully acknowledge Dr Gayle McKellar, a previous contributor to this topic. GM declares that she has no competing interests.

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Associate Director

Medical University of South Carolina

Charleston

SC

利益冲突披露
JCO declares that he has no competing interests.

Professor of Medicine

University of Texas Southwestern Medical Center

Dallas

TX

利益冲突披露
NJO declares that she has no competing interests.

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