BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 六月 2018

小结

定义

病史和查体

其他诊断因素

  • 全身性症状
  • 黄疸
  • 腹水
  • 肝性脑病的症状

危险因素

  • 不安全的医疗实践
  • 静脉或鼻内吸毒
  • 输血或器官移植
  • 1945 年至 1965 年间出生

诊断性检查

首要检查

  • 酶联免疫法或丙肝抗体
  • 核酸扩增检测 (nucleic acid amplification tests, NAATs)
  • 血清转氨酶
  • 病毒基因分型
全部具体信息

需要考虑的检查

  • 非侵入性肝脏纤维化或肝脏弹性测定
  • 肝脏活检
全部具体信息

治疗流程

贡献者

Professor of Medicine

Division of Liver Diseases

Mount Sinai Hospital

New York

NY

利益冲突披露
JA declares that he has no competing interests.

Dr Jawad Ahmad would like to gratefully acknowledge Dr Brian L. Pearlman, the previous contributor to this monograph. BLP is on the speakers’ bureaus and serves as an advisor to Merck, Gilead, J&J, and AbbVie, and does contracted research with Boehringer Ingelheim, Tibotec/Janssen, Bristol-Myers Squibb, Gilead, and Merck. BLP is also an author of a number of references cited in this monograph. BLP wishes to acknowledge Chaithanya Mallikarjun, MD, for her help in writing the original version of the manuscript.

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Assistant Professor

Digestive Disease and Liver Transplant

Yale University

CT

利益冲突披露
AL has participated in an advisory board meeting with Gilead and Janssen, and is a primary investigator for Merck’s C-Surfer trial.

Director of Hepatology and Medical Director of Liver Transplantation

Associate Professor of Medicine

Strong Memorial Hospital

University of Rochester

NY

利益冲突披露
BM belongs to the paid speaker’s bureau for pharmaceutical companies Gilead (maker of ledipasvir/sofosbuvir), AbbVie (maker of Viekira Pak® - ombitasvir/paritaprevir/ritonavir and dasabuvir), Merck, and Salix.

Consultant Hepatologist

Bradford Teaching Hospitals Foundation Trust

Bradford

UK

利益冲突披露
SM has received sponsorship and has sat on advisory boards for BMS, Gilead, AbbVie, and Merck.

Consultant Hepatologist

Nottingham University Hospitals NHS Trust

UK

利益冲突披露
SR is an advisory board (paid) member for AbbVie, Gilead, Janssen, and MSD.

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