前列腺癌是美国癌症的第六大死因,在美国男性中是第二大癌症死因。[7]Siegel RL, Miller KD, Jemal A, et al. Cancer statistics, 2018. CA Cancer J Clin. 2018 Jan;68(1):7-30.https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21442http://www.ncbi.nlm.nih.gov/pubmed/29313949?tool=bestpractice.com 前列腺癌是美国男性最常见的非皮肤恶性肿瘤。
在美国,据估计在 2018 年将会有 164,690 例新发前列腺癌病例,且会有 29,430 例前列腺癌死亡病例。[7]Siegel RL, Miller KD, Jemal A, et al. Cancer statistics, 2018. CA Cancer J Clin. 2018 Jan;68(1):7-30.https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21442http://www.ncbi.nlm.nih.gov/pubmed/29313949?tool=bestpractice.com 在美国,患前列腺癌的终身风险约为 12%。[7]Siegel RL, Miller KD, Jemal A, et al. Cancer statistics, 2018. CA Cancer J Clin. 2018 Jan;68(1):7-30.https://onlinelibrary.wiley.com/doi/full/10.3322/caac.21442http://www.ncbi.nlm.nih.gov/pubmed/29313949?tool=bestpractice.com
2011 至 2015 年间,前列腺癌的确诊年龄中位数 66 岁。[1]National Cancer Institute; Surveillance, Epidemiology, and End Results program (SEER). SEER stat fact sheets: prostate cancer. 2018 [internet publication].http://seer.cancer.gov/statfacts/html/prost.html 同一时期经年龄调整的发病率为每年 112.6 人/100,000 位男性。[1]National Cancer Institute; Surveillance, Epidemiology, and End Results program (SEER). SEER stat fact sheets: prostate cancer. 2018 [internet publication].http://seer.cancer.gov/statfacts/html/prost.html 在白人男性中,发病率为 105.7/100,000,西班牙裔男性的发病率为 91.8/100,000。在世界范围内,黑人男性发病率最高 (178.3/100,000),而美洲印第安人/阿拉斯加原住民男性的发病率最低 (54.8/100,000)。[1]National Cancer Institute; Surveillance, Epidemiology, and End Results program (SEER). SEER stat fact sheets: prostate cancer. 2018 [internet publication].http://seer.cancer.gov/statfacts/html/prost.html
2012 年全球发病率数据显示,澳大利亚和新西兰前列腺癌的发病率最高。[8]International Agency for Research on Cancer. GLOBOCAN: prostate cancer estimated incidence, mortality and prevalence worldwide in 2012. June 2018 [internet publication].http://globocan.iarc.fr/old/FactSheets/cancers/prostate-new.asp