BMJ Best Practice
最后审核时间: 十月 2018
最近更新时间: 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 有变化的色素性皮损(ABCDE指征)
  • 色素性皮损自发出血或溃疡
  • 全身症状
  • >50个良性黑素细胞痣

危险因素

  • 黑素瘤的家族史
  • 黑素瘤的个人史
  • 皮肤癌的个人史(包括日光性损害)
  • 非典型痣的病史

诊断性检查

首要检查

  • 皮肤血管镜检查
  • 皮肤活检
全部具体信息

需要考虑的检查

  • 前哨淋巴结活检
  • 血清乳酸脱氢酶
  • 胸部X线检查
  • 胸、腹、盆腔CT扫描
全部具体信息

新兴检查

  • CDKN2A基因检测
全部具体信息

治疗流程

贡献者

Melanoma Institute Australia

The University of Sydney

Sydney

Australia

利益冲突披露
AMM has received honoraria from Novartis and BMS. AMM is on the advisory boards of MSD and Chugai.

Melanoma Institute Australia

The University of Sydney

Royal Prince Alfred and Mater Hospitals

Sydney

Australia

利益冲突披露
RPMS is on the advisory board for Amgen and has received honoraria from BMS.

Associate Professor of Dermatology

The University of Sydney

Sydney

Australia

利益冲突披露
PF-P declares that he has no competing interests with the topic Melanoma. PF-P has advisory roles with Leo, Novartis, Lilly, Abbvie, Janssen, Celgene (psoriasis, atopic eczema, hidradenitis). He has been paid to do research for Incyte Europe Sarl, and clinical trials for Leo, Janssen, Kyowa Hakko Kirin, Xoma, Akaal, Amgen, Merk. PF-P has also been paid for lectures by Abbvie, Amgen, Lilly, Novartis, Janssen.

Dr Alexander M. Menzies, Dr Robyn P.M. Saw, and Dr Pablo Fernandez-Peñas would like to gratefully acknowledge Dr Philip Friedlander, Dr Hobart W. Walling, and Dr Brian L. Swick, previous contributors to this monograph. PF is a consultant for Genentech. HWW and BLS declare that they have no competing interests.

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Assistant Professor

Department of Pathology and Laboratory Medicine

University of California

Los Angeles

CA

利益冲突披露
DC declares that he has no competing interests.

Dermatologist/Dermatologic Surgeon

President of the South Carolina Skin Cancer Center

Greenville

SC

利益冲突披露
JB declares that he has no competing interests.

Associate Director

JCCC Women's Cancers Program Area

Jonsson Comprehensive Cancer Center at UCLA

Los Angeles

CA

利益冲突披露
MB declares that she has no competing interests.

Medical Director

CancerPartnersUK

London

UK

利益冲突披露
KS declares that he has no competing interests.

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