HELLP 综合征的实验室标准
如要诊断 HELLP 综合征,应当满足下列实验室标准:[1]Sibai BM, Ramadan MK, Usta I, et al. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes and low platelets (HELLP syndrome). Am J Obstet Gynecol. 1993;169:1000-1006.http://www.ncbi.nlm.nih.gov/pubmed/8238109?tool=bestpractice.com[8]Sibai BM. Diagnosis and management of gestational hypertension and preeclampsia. Obstet Gynecol. 2003 Jul;102(1):181-92.http://www.ncbi.nlm.nih.gov/pubmed/12850627?tool=bestpractice.com[18]Martin JN Jr, Rose CH, Briery CM. Understanding and managing HELLP syndrome: the integral role of aggressive glucocorticoids for mother and child. Am J Obstet Gynecol. 2006;195:914-934.http://www.ncbi.nlm.nih.gov/pubmed/16631593?tool=bestpractice.com
溶血,表现为外周血涂片上存在裂红细胞、钝锯齿状红细胞和多染色性。然而,在临床实践中,外周血涂片检查不是常规,可以通过下列方式获得足够的溶血证据:
肝酶升高:AST 和/或 ALT >70 IU/L
血小板减少症:血小板<100,000/μL (<100 x 10⁹/L)。