血压正常的患者,如果有 HELLP 综合征既往史,多达 20% 至 40% 会在随后的妊娠中发生某种形式的先兆子痫。该比例在具有基础高血压疾病者中增加到了 75%。[23]Sibai BL, Ramadan MK, Chari RS, et al. Pregnancies complicated by HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets): subsequent pregnancy outcome and long-term prognosis. Am J Obstet Gynecol. 1995;172:125-129.http://www.ncbi.nlm.nih.gov/pubmed/7847520?tool=bestpractice.com[24]Chames MC, Haddad B, Barton JR, et al. Subsequent pregnancy outcome in women with a history of HELLP syndrome at ≤ 28 weeks of gestation. Am J Obstet Gynecol. 2003;188:1504-1507.http://www.ncbi.nlm.nih.gov/pubmed/12824985?tool=bestpractice.com[25]van Pampus MG, Wolf H, Mayruhu G, et al. Long-term follow-up in patients with a history of (H)ELLP syndrome. Hypertens Pregnancy. 2001;20:15-23.http://www.ncbi.nlm.nih.gov/pubmed/12044310?tool=bestpractice.com[26]Habli M, Eftekhari N, Wiebracht E, et al. Long-term maternal and subsequent pregnancy outcomes 5 years after hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. Am J Obstet Gynecol. 2009;201:385;e1-e5.http://www.ncbi.nlm.nih.gov/pubmed/19716544?tool=bestpractice.com