BMJ Best Practice
最后审核时间: 六月 2019
最近更新时间: 三月 2019

小结

定义

病史和查体

关键诊断因素

  • 存在的危险因素
  • 小肠梗阻
  • 皮肤黏膜色素沉着

其他诊断因素

  • 腹部不适和腹胀
  • 腹痛
  • 腹部不适和腹胀
  • 腹痛

危险因素

  • 阳性家族史
  • STK11基因种系突变

诊断性检查

首要检查

  • 内镜检查
  • 息肉的组织学
  • STK11遗传学检测
全部具体信息

治疗流程

贡献者

Licensed Genetic Counselor

Genomic Medicine Institute

Sanford R. Weiss Center for Hereditary Colorectal Neoplasia

Cleveland Clinic

Cleveland

OH

利益冲突披露
BH declares that she has received payment from the following but has no contractual agreement to disseminate product information for them: Speakers Bureau Myriad Genetics Lab, and the advisory board for Invitae. BH is also President of the Collaborative Group of the Americas on Inherited Colorectal Cancer, for which she does not receive payment.

Victor W. Fazio Chair

Department of Colorectal Surgery

Digestive Disease Institute

Cleveland Clinic

Director

Sanford R. Weiss MD Center for Hereditary Colorectal Neoplasia

Cleveland Clinic

Cleveland

OH

利益冲突披露
JC declares that he has no competing interests.

Director

Center for Colon Polyp and Cancer Prevention

Department of Gastroenterology and Hepatology

Associate Director

Sanford R. Weiss Center for Hereditary Colorectal Neoplasia

Section of Polyposis

Digestive Disease Institute

Cleveland Clinic

Cleveland

OH

利益冲突披露
CAB receives research support from Cancer Prevention Pharmaceuticals.

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Chief of Pediatric Surgery

University of North Carolina

Chapel Hill

NC

利益冲突披露
DVA declares that he has no competing interests.

Consultant in Clinical Genetics

Department of Medical Genetics

Belfast HSC Trust

Belfast

UK

利益冲突披露
PM declares that he has no competing interests.

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