BMJ Best Practice
最后审核时间： 十月 2018
最近更新时间： 一月 2018

小结

定义

病史和查体

关键诊断因素

  • 年轻患者 (MEN1/2)
  • 阳性家族史 (MEN1/2)
  • 偶发出汗、心悸和头痛三联征 (MEN2)
  • 月经不调 (MEN1)
全部具体信息

其他诊断因素

  • 体重变化 (MEN1/2)
  • 高血压 (MEN1/2)
  • 腹痛 (MEN1/2)
  • 头痛 (MEN1/2)
全部具体信息

危险因素

  • MEN 的家族病例
  • RET 原癌基因突变
  • MEN1 (menin) 突变
全部具体信息

诊断性检查

首要检查

  • 血清降钙素 (MEN2)
  • 血清癌胚抗原 (MEN2)
  • 血浆甲氧基肾上腺素 (MEN2)
  • 血清甲状旁腺素和钙 (MEN1/2)
全部具体信息

需要考虑的检查

  • 空腹血糖/胰岛素 (MEN1)
  • 血清 C-肽 (MEN1)
  • 钙刺激性胃泌素 (MEN1)
  • 血清胰岛素原 (MEN1)
全部具体信息

治疗流程

推断

MEN2 家族史

疾病持续状态

MEN1

MEN2

贡献者

作者 查看所有

Research Registrar

Department of Endocrinology

Barts and the London NHS Trust and Queen Mary University of London

London

UK

利益冲突披露
RG declares that she has no competing interests.

Senior Lecturer & Honorary Consultant

Department of Endocrinology

Barts and the London Medical School

London

UK

利益冲突披露
MD declares that she has no competing interests.

Dr Rebecca Gorrigan and Dr Maralyn Druce would like to gratefully acknowledge Dr Jennifer Mammen and Dr Roberto Salvatori, previous contributors to this monograph. JM and RS declare that they have no competing interests.

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Director

Division of Endocrinology and Diabetes

The Children's Hospital of Philadelphia

Philadelphia

PA

利益冲突披露
ML declares that he has no competing interests.

Associate Professor of Endocrinology

Catholic University School of Medicine

Rome

Italy

利益冲突披露
SC declares that he has no competing interests.

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